In this guide, we’re covering Indiana Jones and the Great Circle Secrets of Secrets Puzzle. This puzzle is located in the Sistine Chapel at the Vatican. During this puzzle, you have to figure out the code for the safe. Read on to learn how to solve the Secrets of Secrets puzzle.
Secrets of Secrets Puzzle Location

The Secrets of Secrets puzzle is located in the Sistine Chapel, which is near the bottom of the Vatican City map. You have to go through the Borgia Courtyards to get to the chapel. Once inside, go through the door on the right and up the stairs. The safe is sitting on a table next to the railing on the left.
How to Solve the Puzzle In Indiana Jones and the Great Circle

To begin solving the puzzle, you’ll need to pick up a few things. First, pick up Nicoletti’s Letter. It’s sitting on the table across from the safe. Next, go to the table in the middle of the room, to the left of the safe, and open the left drawer. Pick up the Planetary Chart inside and inspect it. You’ll see various symbols with numbers beside them, a few of which are missing.
Once you have these two notes, go to the small statue of Saint Peter on the small round table to your left. Rotate it and look at the two matching symbols on the bottom. The symbol is the missing one besides the 4 on the chart. Do the same thing with the statue of Saint Paul next to the safe. The symbols here match with the numbers 7 and 1 on the chart.
With these four symbols, you now have the code to the safe: 4471.
That’s it for Indiana Jones and the Great Circle Secrets of Secrets Puzzle. Need more game guides? Check these out!
- Indiana Jones and the Great Circle – Fountain of Confession Puzzle
- Indiana Jones and the Great Circle – Sacred Wounds Puzzle
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