Slay the Spire 2 has three acts, and after completing them all and meeting The Architect, Ascensions are unlocked. Ascensions are a series of modifiers that can make each run significantly harder by strengthening enemies, adding debuffs, and introducing curses.
Here’s everything to know about Slay the Spire 2 Ascensions, including all levels, modifiers, and how to unlock them.
How to unlock ascensions in STS 2?
All players start with zero modifiers, and in order to unlock the first Ascension, they must first defeat the Act 3 boss, such as The Queen, The Test Subject or the Doormaker. After that, they must defeat the Act 3 boss again to advance to the next Ascension.
Note that any Ascension level can be selected as long as it has already been unlocked.
Ascension levels for single-player and multiplayer are separate. Unlocking Ascension 4 in multiplayer does not automatically unlock Ascensions in solo if no Ascensions have been unlocked in single-player.

Solo
For solo runs, each character’s Ascension progress is tracked separately. For example, Ascensions for Necrobinder still need to be unlocked even if Ascension 10 has already been reached on Ironclad.
Multiplayer
This works differently in multiplayer. In multiplayer, Ascension progress is shared across all characters. This means that if Ascension 10 is reached with Necrobinder, Ascension 10 can also be played immediately with Ironclad and other characters.
All 10 Ascensions in Slay the Spire 2 explained
Ascension in Slay the Spire 2 spans 10 levels. Here are all the Ascension levels in Slay the Spire 2 and how they work.
| Level | Ascension | Effect |
|---|---|---|
| 1 | Swarming Elites | This level spawns at least 60% more elites |
| 2 | Weary Traveler | You start with 80% HP, and Ancients will only heal you for that same amount. |
| 3 | Poverty | You receive 25% less gold from enemies and treasure chests. |
| 4 | Tight Belt | Start each run with 1 less potion slot. |
| 5 | Ascender’s Bane | Start each run with the Ascender’s Bane curse card. This card is unplayable, ethereal and eternal. |
| 6 | Gloom | One fewer rest site per act. |
| 7 | Scarcity | Rare and upgraded cards appear half as often, including combat rewards from enemies and the Merchant’s stock. |
| 8 | Tough Enemies | All enemies have increased HP. |
| 9 | Deadly Enemies | All enemies deal increased damage. |
| 10 | Double Boss. | Fight two bosses at the end of Act 3. After defeating one boss, you will have to beat another one again. |
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